Influence of the fcgr2a rs1801274 and fcgr3a rs396991 polymorphisms on response to abatacept in patients with rheumatoid arthritis

HIGHLIGHTS

  • who: Noelia Márquez Pete et al. from the Pharmacy Service, Pharmacogenetics Unit, University Hospital Virgen las Nieves, Granada, Spain have published the paper: Influence of the FCGR2A rs1801274 and FCGR3A rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis, in the Journal: (JOURNAL)
  • what: This study showed that high-affinity FCGR2A-p.131His variant low-affinity FCGR3A-p.158Phe variant and combined use of FCGR2A/FCGR3A genetic variations could affect ABA effectiveness. Within this conceptual framework, the objective of this study was to evaluate the involvement of the FCGR2A rs1801274 and FCGR3A . . .

     

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