Cell surface polysaccharides of bifidobacterium bifidum induce the generation of foxp3+ regulatory t cells

HIGHLIGHTS

• who: Ravi Verma and collaborators from the POSTECH Institutional Animal Care and Use CommitteeA colony of GF C BL/, (B6) mice was established at POSTECH from breeders obtained from A. Macpherson (Bern University, Switzerland) and D. Artis (then at University of Pennsylvania, currently at Cornell University, USA) and maintained in sterile flexible film isolators (Class Biological Clean Ltd., USA). GF status was monitored monthly by culture of cecal contents. Foxp3-eGFP, Tlr2-/-, Tlr4-/-, Tlr6-/-, and MyD88-/- animals were obtained from the Jackson Laboratory. C BL/6-CD45a(Ly5a)-Rag1-/- TCR OT-II (Rag1-/- OT-II TCR transgenic . . .
  

   

  

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