Golgi alpha1,2-mannosidase ia promotes efficient endoplasmic reticulum-associated degradation of nkcc2

HIGHLIGHTS

  • who: Sylvie Demaretz and colleagues from the Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, Paris, FranceDivision of Pediatric Nephrology and Transplantation, University Children's Hospital, Philipps-University have published the Article: Golgi Alpha1,2-Mannosidase IA Promotes Efficient Endoplasmic Reticulum-Associated Degradation of NKCC2, in the Journal: Cells 2022, 101 of 27/Nov/2021
  • what: The authors report the identification of_(ManIA) as a novel binding partner of the immature form of NKCC2. The authors show that ManIA interacts with the immature form of NKCC2 mainly at the cis-Golgi network . . .

     

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