HIGHLIGHTS
- who: Elisa Vitiello from the Université Universidade have published the research: Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Alongside, the authors show that inhibition of acto-myosin contractility impairs centriole separation. The reason of this transient centriole separation is poorly understood. The authors propose a model where acto-myosin forces act as a new regulator of centriole separation and PLK4 recruitment to ensure centriole fidelity (Fig 7). The authors show that a high degree of mechanical polarization significantly affects direction . . .
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