Reduced peroxisome proliferator-activated receptor-α and bile acid nuclear receptor nr1h4/fxr may affect the hepatic immune mi

HIGHLIGHTS

• who: Yingxuan Ma from the Jiao Tong University, China have published the article: Reduced peroxisome proliferator-activated receptor-α and bile acid nuclear receptor NR1H4/FXR may affect the hepatic immune mi, in the Journal: (JOURNAL)
• what: The study demonstrated higher CD56 expression in cluster 2. The experiments showed reduced expression of PPARa and NR1H4 (FXR) mRNAs and proteins in BA liver tissue, while SMAD3 has the opposite trend.
• how: For PPARa and NR1H4 expression the authors used liver biopsy dataset GSE65359 (84 cases of hepatitis B) fetal and adult liver sample dataset GSE61276 . . .
  

   

  

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