HIGHLIGHTS
- who: August and colleagues from the Leipzig University, Germany have published the research: Tetrodotoxin prevents heat-shock induced granule cell dispersion in hippocampal slice cultures, in the Journal: (JOURNAL)
- what: As there is evidence for a relationship between electrical activity and GCD in various epilepsy models, this study aimed to determine whether GCD observed in the heat-shock model could be reduced by blocking electrical activity with the sodium channel blocker tetrodotoxin (TTX). In this study an increased cell number was only observed in the molecular layer in heat-shock treated slice cultures when compared . . .
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