HIGHLIGHTS
- who: Marco Segatto from the Department University of have published the paper: BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Because of this evidence and the well-established role played by BRD4 in inflammation33-35, the authors aimed to characterize BRD4 contribution in skeletal muscle pathophysiology of a mouse model of DMD. The authors show that BRD4 influences ROS metabolism by regulating the transcriptional activation of different subunits of the NADPH oxidase complex in the mdx muscle. The authors show that JQ1 . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.