HIGHLIGHTS
- who: Zhujiang Zhao and collaborators from the Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China have published the research: Depletion of DNMT3A Suppressed Cell Proliferation and Restored PTEN in Hepatocellular Carcinoma Cell, in the Journal: (JOURNAL) of 24/Nov/2009
- what: Received 24 November 2009; Revised 25 February 2010; Accepted 26 February 2010 Promoter hypermethylation mediated by DNA methyltransferases (DNMTs) is the main reason for epigenetic inactivation of tumor suppressor genes (TSGs). The authors attempted to identify tumor-related genes that are potentially regulated by DNMT3A and further discuss . . .
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