Francisella tularensis induces th1 like mait cells conferring protection against systemic and local infection

HIGHLIGHTS

  • who: Zhe Zhao from the Peter Doherty Institute The University of Melbourne, Melbourne, VIC, Australia have published the Article: Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show here that, upon infection, their initial response (accumulation and cytokine secretion) elicited a critical bridging protection role between innate and adaptive immunity. This study shows that MAIT-1 cells have both an innate-like rapid response and adaptive memory-like features, consistent with the previous observations on MAIT-17/1 cells . . .

     

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