Not just a colourful metaphor: modelling the landscape of cellular development using hopfield networks

HIGHLIGHTS

  • who: Atefeh Taherian Fard from the (UNIVERSITY) have published the Article: Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks, in the Journal: (JOURNAL)
  • what: Hopfield model for cellular differentiation Here, the authors aim to link the values of the HN energy function to stages of cellular differentiation. The authors demonstrate that if pair-wise co-expression coefficients are used to construct the weight matrix, these energy values indeed reflect the developmental stages of the cell. Using sets of cells from different stages of differentiation (e_g, pluripotent to differentiated states . . .

     

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