Cytosolic internalization of anti-dna antibodies by human monocytes induces production of pro-inflammatory cytokines independently of the tripartite motif-containing 21 (trim21)-mediated pathway

HIGHLIGHTS

• who: Myung-Hee Kwon from the Konkuk University have published the Article: Cytosolic Internalization of Anti-DNA Antibodies by Human Monocytes Induces Production of Pro-inflammatory Cytokines Independently of the Tripartite Motif-Containing 21 (TRIM21)-Mediated Pathway, in the Journal: (JOURNAL)
• what: The authors show that internalization of an IgG antibody into the cytosol of human monocytes activates cytokine signaling pathways, leading to secretion of pro-inflammatory cytokines.
• how: The study was carried out in accordance with ethical guidelines and recommendations set down by the Research Ethics Committee of Ajou University Hospital. For . . .
  

   

  

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