Wnt-controlled sphingolipids modulate anthrax toxin receptor palmitoylation to regulate oriented mitosis in zebrafish

HIGHLIGHTS

• who: I. Castanon from the Global Health Institute have published the article: Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that sphingolipids control the position of the mitotic spindle during oriented divisions of epiblast cells in zebrafish embryos. The authors show how sphingolipids can regulate a developmental process under the control of signaling molecules.
• how: To create the sptlc1 sgRNA the following oligonucleotides with overhanging ends for BsaI were designed 5u2032-TAGGGGCAACAGTGGGTGTTGG-3u2032 and 5u2032-AAACCCAACACCCACTGTTGCC . . .
  

   

  

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