The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the hla region

HIGHLIGHTS

  • who: Nora Fernandez-Jimenez from the Epigenetics Group, International Agency for Research on Cancer (IARC), Lyon , Lyon, FranceDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country have published the paper: The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region, in the Journal: Scientific Reports Scientific Reports of 13/Dec/2018
  • what: The analysis revealed that the epithelial methylome is characterized by the loss of CpG island (CGI) boundaries often associated to altered gene expression and by the increased variability of the methylation across the samples . . .

     

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