Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding

HIGHLIGHTS

• who: Kevin Wittwer from the Institut State University e, Berlin, Germany have published the research: Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: This study shows the potential of ERDRP-0519 to improve management of severe measles and augment MeV eradication in primates. The authors demonstrate a strong beneficial effect of ERDRP-0519 in MeV-infected squirrel monkeys leading to reduced clinical signs. The authors demonstrate here that ERDRP-0519 treatment does not prevent the generation of humoral immune_responses.
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