Kdm6 demethylase independent loss of histone h3 lysine 27 trimethylation during early embryonic development

HIGHLIGHTS

  • who: Lysine and collaborators from the Department of Genetics, Carolina Center for Genome Sciences, and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina have published the article: KDM6 Demethylase Independent Loss of Histone H3 Lysine 27 Trimethylation during Early Embryonic Development, in the Journal: (JOURNAL) of May/29,/2014
  • what: The authors report that male embryos carrying mutations in both Utx and Jmjd3 survive to term and appear phenotypically normal at mid-gestation.

SUMMARY

    The mammalian embryo undergoes drastic changes in cellular specification and gene_expression programs throughout . . .

     

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