Subthalamic nucleus activity dynamics and limb movement prediction in parkinson’s disease

HIGHLIGHTS

• who: STN = subthalamic nucleus and colleagues from the Patients and surgery We studied the task-related modulation of STN LFPs before and during voluntary upper and lower limb movements in , consecutive Parkinson`s disease patients undergoing STN DBS surgery to improve motor symptoms (clinical details are provided in Supplementary Table, )Recordings were made intraoperatively from both hemispheres, except in seven subjects (Cases, , , and, ) in whom LFPs were recorded in one hemisphere only, due to fatigue and operative constraints. Thus, a total of , hemispheres were studied. Patients were recorded OFF dopaminergic medication. All patients were operated at the . . .
  

   

  

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