Yersinia pestis activates both il-1β and il-1 receptor antagonist to modulate lung inflammation during pneumonic plague

HIGHLIGHTS

• who: Vijay Sivaraman and colleagues from the Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North have published the research: Yersinia pestis Activates Both IL-1u03b2 and IL-1 Receptor Antagonist to Modulate Lung Inflammation during Pneumonic Plague, in the Journal: (JOURNAL) of May/21,/2014
• what: The authors show that IL-1u03b2/IL-18 cytokine activation occurs early after bacteria enter the lung and this activation eventually contributes to pulmonary and pathology the later stages of infection. The authors show that Y. also the induction of IL-1 . . .
  

   

  

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