HIGHLIGHTS
- who: Lei Liu from the (UNIVERSITY) have published the paper: Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance, in the Journal: (JOURNAL)
- what: Our study identified an important ATR-interacting lncRNA, ANRIL, and uncovered its direct mechanism in HR repair of DNA damage: maintaining the stability of the ATR protein.
- how: The data showed that the N terminal of ATR mainly accounted for its interaction with ANRIL (Fig 2C). The data showed that ATR overexpression in ANRIL-KD cells significantly increased . . .
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