The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis

HIGHLIGHTS

  • who: Fibrosis . Collagen . and collaborators from the Department of Pathology and Medical Biology, University of , GZ Groningen, The Netherlands have published the research: The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis, in the Journal: (JOURNAL)
  • what: The authors have stimulated human adult dermal (HDFa) and human adult lung (HLFa) fibroblasts with TGFu03b21 in the presence or absence of CAPE, and investigated the expression and/or synthesis of cytoskeletal components, collagen type I, the collagen-modifying enzyme lysyl hydroxylase 2 (LH2 . . .

     

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