Rnai screening of subtracted transcriptomes reveals tumor suppression by taurine-activated gabaa receptors involved in volume regulation

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  • who: Camiel L. C. Wielders and collaborators from the VU University, Center for Neurogenomics and Cognitive Research, Amsterdam, The Netherlands have published the research work: RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0196979]. May 22, 2018 of /1371/
  • what: The authors show that taurine activates chloride currents through GABAA receptors on MEFs causing seclusion of cell volume in large membrane protrusions. The authors propose that, in addition to p21 induction, tumor suppression involves . . .

     

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