HIGHLIGHTS
- who: Karthik Selvaraju et al. from the Department of Biomedical and Clinical Sciences (BKV), Linku00f6ping University, , Linku00f6ping, Sweden have published the research work: Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System, in the Journal: Biomolecules 2021, 1339 of /2021/
- how: To study the effect of the authors developed a zebrafish PDX model of AML and confirmed antigrowth activity in vivo. The authors used the Broad Institute Library of Integrated Network-Based Cellular Signatures (LINCS) Center for Transcriptomics resource to compare gene_expression profiles induced . . .
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