The maintenance of high affinity plasminogen binding by group a streptococcal plasminogen-binding m-like protein is mediated by arginine and histidine residues within the a1 and a2 repeat domains*

HIGHLIGHTS

• who: Martina L. Sanderson-Smith from the (UNIVERSITY) have published the article: The Maintenance of High Affinity Plasminogen Binding by Group A Streptococcal Plasminogen-binding M-like Protein Is Mediated by Arginine and Histidine Residues within the a1 and a2 Repeat Domains*, in the Journal: (JOURNAL) of April/21,/2006
• what: This study shows for the first time that residues Arg101, Arg114, His102, and His115 in both the a1 and a2 repeat domains of PAM can mediate high affinity plasminogen binding.

SUMMARY

Site-directed mutagenesis of full-length PAM protein from . . .

 



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