Dysregulation of the leukocyte signaling landscape during acute covid-19

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  • who: Isaiah R. Turnbull et al. from the Departments of Surgery, Washington University School of Medicine, StLouis, Missouri, United States of have published the research: Dysregulation of the leukocyte signaling landscape during acute COVID-19, in the Journal: PLOS ONE of February/21,/2022
  • what: Foremost, the study design provides limited clinical information for the cohort of COVID-19 subjects, and the authors have not associated the findings with clinical outcomes from COVID-19. The authors propose that dysregulated STAT3 activation reconciles local inflammation-mediated tissue damage and systemic functional immunosuppression, and suggests that pharmacologic . . .

     

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