HIGHLIGHTS
- who: Posted Date May et al. from the (UNIVERSITY) have published the research work: The zinc ionophore clioquinol reduces Parkinsonu2019s disease patient-derived brain extracts-induced neurodegeneration, in the Journal: (JOURNAL)
- what: The authors aimed to clarify the role of Zn and the modulation of its quantities in a clinically relevant model of PD related to u03b1-syn-induced dopaminergic neurodegeneration. The authors show that in_vivo chronic ClQ exposure can prevent LBtriggered dopaminergic neurodegeneration and reduce u03b1-syn pathology in the SNpc. The study showed that when LB mice were treated with ClQ, the number . . .
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