Chikv infection reprograms codon optimality to favor viral rna translation by altering the trna epitranscriptome

HIGHLIGHTS

• who: Jennifer Jungfleisch from the Universitat Pompeu Fabra, Barcelona, SpainUniversity of have published the article: CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show how CHIKV infection induces a codonspecific reprogramming of the host translation machinery to favor viral protein expression via alterations of the host tRNA epitranscriptome. The authors focused the attention on the ER, where the authors observed dramatic changes (Fig 2d).
• how: A similar observation was obtained by overexpressing KIAA1456 under translational stress . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.