HIGHLIGHTS
- who: Su00e9verine Guiu from the (UNIVERSITY) have published the research: Prognostic value of androgen receptor and FOXA1 co-expression in non-metastatic triple negative breast cancer and correlation with other biomarkers, in the Journal: (JOURNAL)
SUMMARY
Triple negative breast cancers (TNBCs) represent 15% of all breast cancer (BC) and are defined by the lack of oestrogen receptor (ER), progesterone receptor (PR) and HER2 expression/amplification. In LAR tumours, AR functionality is dependent on FOXA1: FOXA1 is required for AR binding chromatin, AR transcriptional activity and cell growth, directing AR to sites normally occupied . . .
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