HIGHLIGHTS
- who: Colorectal Cancer and colleagues from the Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America, StVincent`s University Hospital, Dublin, Ireland have published the paper: Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer, in the Journal: (JOURNAL) of March/20,/2012
- what: The authors demonstrate that the lower random mutation frequency in tumor tissue was also coupled with a shift in glucose metabolism from oxidative phosphorylation to anaerobic glycolysis as compared to non-neoplastic colon. The experiments described here expose a surprising paradox in cancer biology.
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