Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the wnt and tgf-β1 pathways in ivf embryos

HIGHLIGHTS

  • who: Yue Huang from the Animals Adult Kun-Ming mice (male:, months old have published the paper: Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-u03b21 pathways in IVF embryos, in the Journal: (JOURNAL) of 30/Nov/2021
  • what: In this study, using a well-established model of oxidatively damaged IVF mouse embryos, the authors aimed to explore the relevant mechanisms of tumorigenesis in IVF-derived offspring, especially the effects of ROS on ribosome biogenesis closely related to tumorigenesis. The authors show, for the . . .

     

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