HIGHLIGHTS
- who: Br. J. Cancer and collaborators from the Division121, CX Amsterdam, The Netherlands have published the Article: (1985) 659-663 Primary hypothyroidism in breast patients with irradiated supraclavicular lymph nodes, in the Journal: (JOURNAL)
- how: When the authors studied the merits of aminoglutethimide for the treatment of metastatic breast in postmenopausal women in a phase II clinical trial the authors were confronted with an incidence of manifest myxedema in 25% and of subclinical hypothyroidism still compensated by a rise of serum thyrotropin (TSH) in 78% of the patients after 8 weeks (Bruning et_al 1984).
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