An 89zr-hdl pet tracer monitors response to a csf1r inhibitor

HIGHLIGHTS

  • who: BRIEF COMMUNICATION and collaborators from the Institut Eindhoven University have published the paper: An 89Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor, in the Journal: (JOURNAL)
  • what: The authors propose an 89Zr-labeled high-density lipoprotein (89Zr-HDL) nanotracer as a means of monitoring response to immunotherapy. The authors explore the use of 89Zr-labeled reconstituted HDL as a macrophage-targeted diagnostic tool that might help clinicians more quickly and accurately assess the response to anti-TAM immunotherapies. This analysis showed a significantly lower radioactivity deposition in tumors from PLX3397-treated mice . . .

     

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