Identification and characterization of enhancer-blocking insulators to reduce retroviral vector genotoxicity

HIGHLIGHTS

  • who: Amy C. Groth and collaborators from the Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington, United States of America, Department of Genome have published the paper: Identification and Characterization of Enhancer-Blocking Insulators to Reduce Retroviral Vector Genotoxicity, in the Journal: PLOS ONE | www.plosone.org of August/31,/2013
  • what: This activity has only been demonstrated in studies using a combination of the CTCF binding_sites from the cHS4 and BEAD-1 insulators that have no barrier insulator activity , or the full-length 1.2 kb version of the cHS4 . . .

     

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