Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models

HIGHLIGHTS

  • who: Ellie M. Chilcott from the (UNIVERSITY) have published the research: Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models, in the Journal: (JOURNAL) of 22/04/2020
  • what: The authors discuss how effectively preclinical data can predict clinical trial outcome. This approach has proven successful in other recent pre-clinical meta-analyses and has shown to be comparable to standard (hazard or odds ratio) techniques .
  • how: If studies presented multiple control groups the following hierarchy was implemented and data were extracted Gene . . .

     

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