HIGHLIGHTS
- who: Giuseppe Filomeni from the DepartmentTor Vergata University of Cancer Society Research Center, Copenhagen, Denmark have published the Article: TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial S-Nitrosylation, in the Journal: (JOURNAL) of 29/04/2020
SUMMARY
At variance with the other members, TRAP1 (i) shows a marked asymmetric conformation; (ii) can use both Ca2+ and Mg2+ as cofactors; and_(iii) aids substrate folding without co-chaperone assistance, this making it unique among Hsp90 family members (Lavery et_al, 2014; Masgras et_al, 2017b; Elnatan and Agard, 2018). This effect can be both . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.