Trna fragments populations analysis in mutants affecting trnas processing and trna methylation

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  • who: Anahi Molla-Herman and Christophe Antoniewski from the University College Cork, Ireland United States have published the paper: tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation, in the Journal: (JOURNAL)
  • what: The analysis shows that tRNA processing defects alter tRFs biogenesis and/or stability in Rpp30 mutants: increase of_(50 -tRFs, i-tRFs and 30 tRFs), and tRFs-1 decrease. The authors provide a new genome reference, comprising sequences upstream and downstream of mature tRNA genome sequences and bioinformatically added CCA tags that allow analysis of 30 -tRFs and 50 . . .

     

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