Combined transcriptomic and proteomic analysis of perk toxicity pathways

HIGHLIGHTS

  • who: Rebeka Popovic and collaborators from the MRC Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Road, Cambridge , QR, UK have published the research: Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways, in the Journal: (JOURNAL) of 26/04/2021
  • what: The authors microarray analysis and quantitative proteomics analysis in adult flies overexpressing dPerk to investigate the relationship between the transcriptional and translational response to dPerk activation. The authors show that dPerk upregulation promotes the translation of a limited set of mRNAs, that function to resolve stress; these mRNAs include transcripts from the . . .

     

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