HIGHLIGHTS
- who: Uzi Gileadi from the (UNIVERSITY) have published the article: Membrane Topology of the ATP-binding Cassette Transporter Associated with Antigen Presentation (Tap1) Expressed in Escherichia coli*, in the Journal: (JOURNAL) of August/19,/1996
- how: This approach and the related phoA method have been used successfully to study many other membrane_proteins .
SUMMARY
The ATP-binding cassette transporters associated with antigen presentation (Tap1 and Tap2) mediate the transport of peptide fragments across the endoplasmic_reticulum membrane of mammalian cells. From these data a topological model can be derived in which Tap1 spans . . .
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