HIGHLIGHTS
- who: Brief communication and colleagues from the University of Edinburgh Centre UK have published the paper: Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation, in the Journal: (JOURNAL)
- what: The authors propose that targeting Mcl-1 may be beneficial in treatment of allergic airway disease. The authors report several novel findings that extend the understanding of eosinophil apoptosis in controlling inflammation and tissue injury in airway allergy. The authors show that overexpression of Mcl-1 leads to exacerbated allergic airway inflammation as determined by several inflammation parameters including BALF cellularity, eosinophil numbers . . .
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