Erk-induced activation of tcf family of srf cofactors initiates a chromatin modification cascade associated with transcription

HIGHLIGHTS

• who: Cyril Esnault from the Francis Crick Institute, Midland Road, London , AT, UK have published the paper: ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription, in the Journal: (JOURNAL) of March/16,/2017
• what: The authors investigated the relationship among ERK signaling histone modifications and transcription factor activity focusing on the ERK-regulated ternary complex factor family of SRF partner proteins. Using the approach presented above, the authors identified TPA-induced changes at sequences previously defined as DNase I HS in mouse fibroblasts (see STAR Methods . . .
  

   

  

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