A novel exchange method to access sulfated molecules

HIGHLIGHTS

  • who: Jaber A. Alshehri from the SchoolUniversity of have published the article: A novel exchange method to access sulfated molecules, in the Journal: Scientific Reports Scientific Reports
  • how: In comparison to the previous methodology using TBSAB the following observations were identified 8a (99% vs 98%) 8d (90% vs 97%) 8e (98% vs 61%) 8f (93% vs 87%) and 8g (99% vs 85%).

SUMMARY

    Optimised benzylamine sulfamation conditions. (entry 5 vs entry 4) resulted in quantitative conversion to the pyridinium salt. Using the optimal conversion conditions (entry 5) a variety of lipophilic . . .

     

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