New anti-candida active nitrogen-containing bisphosphonates as inhibitors of farnesyl pyrophosphate synthase candida albicans

HIGHLIGHTS

  • who: UDC and collaborators from the National Academy of have published the research work: New aNti-caNdida active NitrogeN-coNtaiNiNg bisphosphoNates as iNhibitors of farNesyl pyrophosphate syNthase Candida albicans, in the Journal: (JOURNAL) of 05/02/2019
  • what: In the work , the developed predictive QSAR models for the inhibition activities of N-BPs against FPPS from L major using a data set of 97 compounds were presented. The authors demonstrate the creau00ad ted homology FPPS C. albicans model and the dockingu00adanalysis of active anti-Candida N-BPs into its active center as the confirmation of . . .

     

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