Idelalisib improves cd37 antibody bi 836826 cytotoxicity against chemo-resistant /relapse-initiating cll cells: a rationale for combination treatment

HIGHLIGHTS

  • who: S Betrian from the (UNIVERSITY) have published the article: Idelalisib improves CD37 antibody BI 836826 cytotoxicity against chemo-resistant /relapse-initiating CLL cells: a rationale for combination treatment, in the Journal: (JOURNAL)
  • what: The authors assessed the efficacy of BI 836826 on global and chemoresistant SP B-cell depletion from relapsed CLL patient`s samples ex vivo (Supplementary Information 1).
  • how: The authors collected samples from relapsed patients mainly after FR/FCR treatment and from a phase I clinical study with BI 836826 monotherapy for CLL patients.

SUMMARY

     

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