HIGHLIGHTS
- who: Dan Xia from the DepartmentPeking University Road, Linyi, China have published the research work: Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress, in the Journal: (JOURNAL)
- what: The authors demonstrate that knockout of MARCH2 using CRISPR/Cas9 gene editing biotechnology suppressed the growth of colon cancer cells in_vitro and in_vivo via effects associated with the ER stress pathway.
- how: The number of GFP-LC3B puncta per cell was assessed in 50 cells and statistical data were obtained from three independent experiments.
SUMMARY . . .
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