Novel 4-azapregnene derivatives as potential anticancer agents: synthesis, antiproliferative activity and molecular docking studies

HIGHLIGHTS

  • who: Vanessa Brito and colleagues from the Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, AvInfante DHenrique have published the research work: Novel 4-Azapregnene Derivatives as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies, in the Journal: Molecules 2022, 6126 of 12/08/2022
  • what: This research showed interesting results, with some of these steroids presenting very potent effects especially against colon (HCT-15) and breast (MCF-7) cancer cells .

SUMMARY

    A research study reported the synthesis of 4-azasteroidal purine nucleoside analogs and their evaluation . . .

     

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