HIGHLIGHTS
- who: TYPE and colleagues from the National University of, United Kingdom have published the Article: Controlled human infectious models, a path forward in uncovering immunological correlates of protection: Lessons from enteric fevers studies, in the Journal: (JOURNAL)
- what: Interestingly, this study examined the expression of integrin u03b14u03b27 on circulating monocytes and found an upregulation of integrin u03b14u03b27 in TD volunteers after challenge, but not in NoTD volunteers . This study determined the binding/interaction of monocytes and DC to S. Typhi-infected cells. To address this further, another typhoid CHIM study was conducted to examine the . . .
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