HIGHLIGHTS
- who: Jianyong Zhong and colleagues from the DepartmentVanderbilt University Nashville, Tennessee, USA have published the research: Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury, in the Journal: (JOURNAL)
SUMMARY
The beneficial effects of HDL have been extensively studied in cells involved in atherosclerosis, such as macrophages and endothelial cells. Recent emphasis has shifted from the quantity of HDL to the functionality of the HDL particles, which is affected by structural and chemical changes transforming the lipoproteins into harmful molecules. A key mechanism in the transformation involves reactive carbonyls formed from peroxidation of arachidonic . . .
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