Functional repercussions of hypoxia-inducible factor-2 in idiopathic pulmonary fibrosis

HIGHLIGHTS

  • who: Ana Karen Torres-Soria and colleagues from the Facultad Estudios Superiores Iztacala Universidad Nacional Autu00f3noma Mu00e9xico, Mexico City, Mexico have published the paper: Functional Repercussions of Hypoxia-Inducible Factor-2 in Idiopathic Pulmonary Fibrosis, in the Journal: Cells 2022, 11, 2938. of /2022/
  • what: In this review the authors focused on the impact of hypoxia in the physiopathology of idiopathic pulmonary fibrosis (IPF) related to lung development regeneration and repair. The authors propose that hypoxia-inducible transcription factor 2a (HIF-2u03b1) is part of the persistent aberrant regeneration associated with developing IPF.
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