The escape of candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways

HIGHLIGHTS

• who: Franu00e7ios A.B. Olivier from the Biomedicine Discovery Institute Monash University VIC, Australia have published the Article: The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways, in the Journal: (JOURNAL) of September/20,/2022
• what: To better define mechanisms here the authors develop an imaging assay to directly and dynamically quantify hyphal and correlate it to macrophage responses. assay reveals escapes by using two proteins to permeabilize macrophage membranes: fungal candidalysin and Nlrp3 inflammasome-activated Gasdermin D. Candidalysin plays major role with Nlrp3 . . .
  

   

  

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