Inhibition of cebpb attenuates lupus nephritis via regulating pim-1 signaling

HIGHLIGHTS

  • who: Pim- and colleagues from the Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, #, Jianshe East Road, Zhengzhou, Henan, China have published the research work: Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling, in the Journal: Mediators of Inflammation of 20/09/2022
  • what: The authors identified that knockdown of CEBPB alleviated the development of LN, suppressed the activation of the inflammasome, and downregulated the expression of Pim-1 in mouse and glomerular podocytes.
  • how: In this study MRL/lpr mice and MRL/MPJ mice were used to . . .

     

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