Influence of denaturants on amyloid b42 aggregation kinetics

HIGHLIGHTS

  • who: Sara Linse from the University of Kent, United Kingdom have published the research work: Influence of denaturants on amyloid b42 aggregation kinetics, in the Journal: (JOURNAL)
  • what: The authors examine how the different steps of the Au03b242 aggregation process are affected by denaturants through a combined experimental and theoretical approach. By utilising a natively unfolded peptide, the authors aim to advance the mechanistic understanding of the aggregation process without convolution with the unfolding step sometimes required for a natively folded protein. At high urea concentration, the authors show here fitting to the onset of . . .

     

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