Identification of a thyroid hormone derivative as a pleiotropic agent for the treatment of alzheimer’s disease

HIGHLIGHTS

  • who: Massimiliano Runfola and collaborators from the Department of Pharmacy, University of Pisa, Via Bonanno, Pisa, Italy have published the article: Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimeru2019s Disease, in the Journal: Pharmaceuticals 2021, 1330 of 24/06/2020
  • what: The authors demonstrate herein that SG2 acts in a pleiotropic manner to induce recovery in a C. elegans model of AD based on the overexpression of Au03b242 and improves learning abilities in the 5XFAD mouse model of AD. To confirm the beneficial effects of SG2 against Au03b2 . . .

     

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